Isis Venture Partners

Isis Venture Partners was founded by Brian Waterman. His wealth derives from founding and serving as CEO of Risk Management Solutions (RMS), a catastrophe risk modeling firm he grew from a Stanford research project into an essential tool for the global insurance industry. RMS was acquired by Daily Mail and General Trust plc in 2000.

The firm sources primarily through Brian Waterman's long-established network in the insurance, enterprise software, and risk analytics sectors. Given his operating background at RMS, warm introductions from within the insurtech and enterprise data ecosystems are the primary conduit for deal flow. The firm does not operate a traditional outbound sourcing engine.

Isis Venture Partners focuses on early-stage, direct equity investments in enterprise software and data companies. The firm is particularly active in insurance technology and financial technology but will invest in any data-intensive enterprise software business where Waterman's operating experience as the founder of RMS provides a competitive diligence or value-creation advantage.

Isis Venture Partners operates as the single-family office investment vehicle for Brian Waterman. It does not raise outside limited-partner capital through blind-pool fund structures, funding its venture commitments directly from the principal's personal capital. This allows for flexible hold periods and the absence of a fixed fund-return horizon.

The firm can lead or co-invest, depending on the specific deal. Its early-stage focus and single-principal structure make it a natural co-investor alongside seed funds and other domain-expert angels in data-centric insurance and enterprise deals. Brian Waterman's personal track record and sector authority often provide the technical credibility required to anchor a competitive round.