# JAZZ Venture Partners

JAZZ Venture Partners is a Venture Capital based in San Francisco, United States.

## Overview

- **Organization type:** Venture Capital
- **Headquarters:** San Francisco, United States
- **Region:** North America
- **Address:** San Francisco, CA, United States
- **Founded:** 2015
- **Assets under management:** Undisclosed
- **Website:** jazzvp.com
- **LinkedIn:** https://www.linkedin.com/company/jazz-venture-partners

## Regulatory record

- **CRD number:** 277092
- **SEC file number:** 802-106693
- **Registration status:** Registered
- **Latest Form ADV filing:** 2026-03-31T05:00:00.000Z
- **Reports private funds:** Yes
- **Private funds reported:** 0
- **IAPD record:** https://adviserinfo.sec.gov/firm/summary/277092

## About

JAZZ Venture Partners invests in technologies that improve human performance. JAZZ seeks breakthroughs at the convergence of technology, science, and humanity — improving how we live, work, and experience the world. The firm is a team of experienced operators, technologists, scientists, and entrepreneurs who work together to make a positive difference.

## Sectors

- Digital Health
- AI/ML
- Neuroscience
- Consumer Tech
- Enterprise Software

## People

- John Spinale — Co-Founder & Managing Partner
- Zack Lynch — Co-Founder & Managing Partner

## Questions

### Who runs investment decisions at JAZZ Venture Partners?

Investment decisions are led by co-founders and managing partners John Spinale and Zack Lynch. Spinale brings operating experience scaling consumer platforms, including as a former executive at Disney's Club Penguin. Lynch authored The Neuro Revolution (2009) and founded the Neurotechnology Industry Organization, bringing the neurotech thesis depth to the partnership.

### What does 'human augmentation' mean in JAZZ Venture Partners' investment thesis?

The firm defines human augmentation as technology that measurably improves human cognition, physical performance, recovery, or mental health through a direct interface with brain function or neural pathways. This spans neurostimulation devices, digital therapeutics for conditions like depression and chronic pain, sleep optimization platforms, and cognitive training software. The common requirement is a mechanistic link to neuroscience — pure wellness apps or fitness trackers without a clinical or neural evidence basis fall outside the thesis.

### Does JAZZ Venture Partners invest only in healthcare companies?

No. While digital health and digital therapeutics are core, JAZZ also invests in consumer performance platforms, professional athlete training tools, and wellness technology. The unifying thread is neuroscience and human performance, not a specific regulatory category. Portfolio company Aura Health, for instance, is a consumer meditation and sleep app, while Halo Neuroscience (acquired) sold a neurostimulation headset to both elite athletes and general consumers.

### What investment stages does JAZZ Venture Partners target?

JAZZ invests from seed through growth stages, with a preference for leading or co-leading rounds. Early checks target companies translating lab-stage neuroscience into a commercial prototype, while growth investments back companies with clinical validation and early revenue that are scaling toward FDA clearance or mass consumer adoption.

### How is JAZZ Venture Partners different from other digital health venture firms?

Most digital health firms evaluate companies through a clinical or payer-economics lens. JAZZ adds a mandatory neuroscience screen — the firm requires that a portfolio company's mechanism of action be traceable to a specific neural or brain-function pathway. This screens out many general telehealth and EHR companies while pulling in non-traditional health deals like neuro-gaming and elite sports performance.

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- [Jaza Rift Ventures](https://altss.com/profile/jaza-rift-ventures)
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Last updated: 2026-08-11T15:07:12.582Z

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