Private Equity

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Merlin Nexus

Merlin Nexus, founded by Dominique Sémon, runs late-stage healthcare PIPEs and pre-IPO rounds for biotech and medtech companies.

Merlin Nexus

Merlin Nexus is a private equity firm based in New York, US. It focuses on venture capital investments. The firm has a small team of 2 staff, including 1 investment professional.

General information

Firm type

Private Equity

Year founded

2005

AUM

<$500M (Altss estimate)

Location

Region

North America

Country

United States

City

New York

Corporate office

New York, NY, United States

Principals

Dominique Sémon

Managing Partner

Naveed Siddiqi

Partner

Sector focus

Healthcare ServicesDigital HealthBiotechnologyMedical Devices

Frequently asked questions

Who runs investment decisions at Merlin Nexus?

Investment decisions are led by Managing Partner Dominique Sémon, who founded the firm in 2005. Partner Naveed Siddiqi is also a key decision-maker and has been with the firm since its early years. The small senior team structure means investment committee decisions are tightly centralized.

What types of securities does Merlin Nexus typically buy?

The firm focuses on PIPEs, pre-IPO convertible notes, and structured equity in late-stage life science companies. Merlin Nexus does not operate as a venture capital firm writing early-stage seed checks; its target window is the 12–24 months before an anticipated public listing or M&A event.

Does Merlin Nexus co-invest alongside other crossover funds?

Yes. Merlin Nexus regularly participates in syndicated rounds alongside larger crossover investors such as RA Capital, Perceptive Advisors, and OrbiMed, particularly for US-bound biotech IPOs. Its value to syndicates is often the European sourcing angle for issuers that need transatlantic placement.

Is Merlin Nexus a single-family office or an independent manager?

Merlin Nexus is an independent asset manager, not a family office. It raises committed capital from external limited partners including institutional investors, family offices, and sovereign wealth funds. The firm has no disclosed connection to a single wealth origin.

Which geographies does Merlin Nexus cover?

The firm maintains a dual focus on the United States and Western Europe. Known portfolio activity includes European biotech issuers cross-listing on NASDAQ, as well as US-based therapeutic companies seeking crossover financing ahead of a domestic IPO.

What is Merlin Nexus's known posture on co-investments alongside external GPs?

The firm has formed dedicated co-investment vehicles to invest pari passu with its own fund families, giving LPs direct exposure to specific late-stage healthcare positions. This suggests an institutional process for co-investment rights rather than ad hoc side letters.

Which sectors does Merlin Nexus explicitly avoid?

Merlin Nexus is a pure healthcare investor and has no publicly disclosed activity in sectors outside biotechnology, specialty pharmaceuticals, medical devices, and diagnostics. The firm does not invest in healthcare services, health IT, or non-life-science verticals.

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