# Methuselah Foundation

Methuselah Foundation is a Nonprofit Foundation based in Palo Alto, United States.

## Overview

- **Organization type:** Nonprofit Foundation
- **Headquarters:** Palo Alto, United States
- **Region:** North America
- **Address:** Palo Alto, CA, United States
- **Founded:** 2003
- **Assets under management:** Undisclosed
- **Website:** methuselahfoundation.org
- **LinkedIn:** https://www.linkedin.com/company/methuselah-foundation

## Regulatory record

- **Reports private funds:** No

## About

Methuselah Foundation was co-founded by Dave Gobel and Aubrey de Grey in 2003. The organization focuses on aging research and life extension. Methuselah Foundation has made five investments, including a grant to Oisin Biotechnologies on December 18, 2024.

## Sectors

- Longevity
- Biotechnology
- Healthcare Services
- AgriTech & FoodTech
- AI/ML

## Offices

- San Francisco, CA, United States
- Leipzig, Germany
- Graz, Austria
- Hingham, MA, United States
- Schwyz, Switzerland

## People

- Aubrey de Grey — Co-Founder and Chief Science Officer
- David Gobel — Co-Founder and CEO

## Questions

### Who founded the Methuselah Foundation and how is it governed?

The Methuselah Foundation was co-founded in 2003 by Aubrey de Grey and David Gobel. De Grey serves as Chief Science Officer, setting the SENS research agenda, while Gobel is CEO, overseeing operations. The organization is a 501(c)(3) nonprofit governed by a board of directors.

### What is SENS and how does it guide the foundation's investments?

SENS (Strategies for Engineered Negligible Senescence) is a framework developed by de Grey that classifies age-related damage into seven categories — including mitochondrial mutations, cell loss, and extracellular crosslinks — and proposes repair therapies. The foundation funds research projects aligned with these categories, often through grants or prize competitions.

### Does the Methuselah Foundation invest directly in for-profit companies?

Yes, the foundation operates a hybrid model: it makes grants and awards prizes to academic labs, but also spins out or invests in for-profit entities such as AgeX Therapeutics and the Longevity Fund. These vehicles are intended to commercialize SENS-based therapies and generate returns that can be recycled into further research.

### How does the foundation relate to the SENS Research Foundation?

The SENS Research Foundation (SRF) was a separate nonprofit focused on advancing SENS science. In November 2020, the Methuselah Foundation and SRF agreed to merge their research operations, consolidating efforts under a single entity (per the foundation's communiqué, November 2020). The Methuselah Foundation now coordinates the combined research programs.

### What geographic regions does the Methuselah Foundation operate in?

The foundation is headquartered in Palo Alto, California, with offices in San Francisco, Leipzig (Germany), Graz (Austria), Hingham (Massachusetts), and Schwyz (Switzerland). Its research grants and prize programs fund scientists globally, but the majority of funded labs are in the United States and Europe.

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Last updated: 2026-06-03T20:00:00.000Z

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