# ONCE Ventures

ONCE Ventures is a Venture Capital based in Sherman Oaks, United States.

## Overview

- **Organization type:** Venture Capital
- **Headquarters:** Sherman Oaks, United States
- **Region:** North America
- **Address:** Sherman Oaks, CA, United States
- **Founded:** 2020
- **Assets under management:** Undisclosed
- **Website:** onceventures.com
- **LinkedIn:** https://www.linkedin.com/company/once-ventures

## Regulatory record

- **Reports private funds:** No

## About

ONCE Ventures (Otsuka Nutraceutical Emerging Ventures) searches for companies that deliver meaningful improvements to consumer health. Its focus is on innovations that align with Otsuka’s mission to create and maintain better health worldwide. It invests in areas including longevity, microbiome, personalized nutrition, mental wellness, and women’s health.

## Sectors

- Digital Health
- Healthcare Services
- AgriTech & FoodTech

## People

- Ara Abrahamian — Managing Director
- Andrew Goodman — Investment Director

## Questions

### Who runs investment decisions at ONCE Ventures?

Managing Director Ara Abrahamian leads the investment team, with Investment Director Andrew Goodman serving as the next senior decision-maker. The firm lists six investment professionals on its public team page, operating from the Sherman Oaks headquarters.

### How is ONCE Ventures related to Otsuka Pharmaceutical?

ONCE Ventures is the corporate venture capital arm of Otsuka, specifically housed within its North American nutraceutical division. It invests in consumer-health startups that align with Otsuka's existing over-the-counter supplement and functional-food brands, leveraging the parent company's R&D, manufacturing, and retail relationships.

### Which sectors does ONCE Ventures explicitly invest in?

Five focus areas are named: longevity science, the microbiome, personalized nutrition, mental wellness, and women's health. The firm also maintains an open category for scientifically differentiated medical foods, supplements, digital health solutions, and consumer devices available without a prescription.

### Does ONCE Ventures invest outside North America?

No. The firm's stated criteria require portfolio companies to be located in or focused on North America. The parent company, Otsuka, is headquartered in Japan, but ONCE Ventures invests strictly within its North American nutraceutical mandate.

### What strategic advantages does ONCE Ventures offer beyond capital?

Portfolio companies gain access to Otsuka's proprietary retail relationships, cross-channel go-to-market strategy capabilities, clinical research design, intellectual property protection, and regulatory expertise. The firm markets this as a built-in commercial infrastructure, distinct from a purely financial VC.

## Related profiles

- [On.Capital](https://altss.com/profile/on-capital)
- [Oncology Ventures](https://altss.com/profile/oncology-ventures)

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Last updated: 2026-08-11T15:07:41.444Z

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