# Opal Ventures

Opal Ventures is a Venture Capital based in New York, United States.

## Overview

- **Organization type:** Venture Capital
- **Headquarters:** New York, United States
- **Region:** North America
- **Address:** New York, NY, United States
- **Founded:** 2025
- **Assets under management:** Undisclosed
- **Website:** opalventures.com
- **LinkedIn:** https://www.linkedin.com/company/opal-ventures

## Regulatory record

- **Reports private funds:** No

## About

Opal Ventures are thesis-driven investors backing health tech startups working to transform healthcare in the US. They focus on pre-seed stage investments with check sizes of $100k-$200k and are happy to be the first check into promising startups. As past operators, they roll up their sleeves to help founders execute and foster trust and transparency with portfolio companies.

## Sectors

- Digital Health
- Healthcare Services

## Offices

- New Haven, CT
- Emeryville, CA

## People

- Owen Willis — Founder and General Partner
- Matthew Magnani — Investment Analyst

## Questions

### What investment stages does Opal Ventures target?

Opal invests primarily at seed and Series A, where its clinical domain expertise has the highest marginal value relative to generalist funds. The firm takes board or observer seats alongside lead investors in most deals. It does not publicly participate in growth-stage rounds or pre-seed exploration vehicles.

### How does Opal source proprietary deal flow?

Opal sources through clinical networks, academic medical centers, and physician-founder referrals — channels that are difficult for non-clinician investors to replicate. Both partners maintain ties to major health systems and teaching hospitals, giving them early visibility into founders who are building solutions to problems they've encountered in practice.

### Does Opal participate in fund commitments or only direct deals?

Based on public record, Opal invests directly into operating companies and does not market a fund-of-funds program. The firm's model is concentrated on primary equity positions in health-tech startups rather than commitments to external venture funds.

### Which sectors does Opal explicitly avoid?

Opal does not invest in traditional biotech, pharmaceutical development, or medical devices that lack a software or data component. The firm's narrow mandate excludes anything where clinical expertise alone cannot provide a diligence edge over non-physician investors.

## Related profiles

- [World Insurance Associates](https://altss.com/profile/world-insurance-associates-llc)

---

Last updated: 2026-08-11T15:07:41.444Z

Canonical page: https://altss.com/profile/opal-ventures

Maintained by Altss — https://altss.com — methodology: https://altss.com/methodology