# Over-the-Rhine Ventures

Over-the-Rhine Ventures is a Venture Capital based in Cincinnati, United States.

## Overview

- **Organization type:** Venture Capital
- **Headquarters:** Cincinnati, United States
- **Region:** North America
- **Address:** Cincinnati, OH, United States
- **Assets under management:** Undisclosed
- **Website:** otrfoundation.org

## Regulatory record

- **Reports private funds:** No

## About

The Over-the-Rhine Foundation (OTRF) is a Cincinnati, Ohio-based organization founded in 1992. It focuses on historically significant neighborhoods. OTRF's investment arm, Over the Rhine Ventures, has made one investment: in Orthogon Therapeutics as part of their Series A on March 08, 2018.

## Offices

- Boston, MA, United States

## Questions

### What is Over-the-Rhine Ventures' investment focus?

Over-the-Rhine Ventures' specific sector focus and stage preferences have not been disclosed publicly. The firm's name references the Over-the-Rhine neighborhood in Cincinnati, but no official materials confirm a regional or thematic mandate.

### Who runs investment decisions at Over-the-Rhine Ventures?

The firm's principals and investment committee members are not named in public sources. No leadership team is listed on any available platforms.

### What portfolio companies has Over-the-Rhine Ventures backed?

No portfolio companies or investments have been publicly attributed to Over-the-Rhine Ventures. This lack of disclosure makes it difficult to evaluate deal track record or sector exposure.

### How does Over-the-Rhine Ventures source deals?

The firm's deal origination model is not publicly described. Without disclosed team or strategy, sourcing methodology remains unknown.

### Is Over-the-Rhine Ventures open to co-investments or fund commitments?

The firm's posture on co-investments or fund-of-funds relationships has not been stated. No information is available on capital access or partnership structures.

### Where is Over-the-Rhine Ventures registered or located?

The firm has offices in Cincinnati, Ohio, and Boston, Massachusetts, United States. No additional international offices have been identified.

## Related profiles

- [TRI Ventures](https://altss.com/profile/tri-ventures)
- [Trackers](https://altss.com/profile/trackers)

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Last updated: 2026-06-03T20:00:00.000Z

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