# Palo Alto Investors

Palo Alto Investors is an Asset Manager based in Palo Alto, United States.

## Overview

- **Organization type:** Asset Manager
- **Headquarters:** Palo Alto, United States
- **Region:** North America
- **Address:** Palo Alto, CA, United States
- **Founded:** 1989
- **Assets under management:** Undisclosed
- **Website:** pa-investors.com
- **LinkedIn:** https://www.linkedin.com/company/palo-alto-investors

## Regulatory record

- **CRD number:** 109171
- **SEC file number:** 801-58166
- **Registration status:** Registered
- **Reports private funds:** Yes
- **IAPD record:** https://adviserinfo.sec.gov/firm/summary/109171

## About

Palo Alto Investors is an SEC-registered investment adviser in Palo Alto, CA, registered since 2000. The firm manages approximately $696 million in assets. It has 10 employees and 4 investment advisers.

## Questions

### Who runs investment decisions at Palo Alto Investors?

The firm has not publicly named its current investment committee or portfolio managers on its website. The founding team established the physician-led structure in 1989, but individual decision-making roles are not disclosed in available primary materials.

### What is Palo Alto Investors' stated investment philosophy?

The firm tells prospective clients it conducts "exhaustive research" to identify long-term investments and states plainly: "We don't rent stocks. We own them." That signals low turnover and a commitment to holding periods that run across market cycles, guided by original, fundamental work.

### Is Palo Alto Investors a hedge fund or a long-only manager?

Available materials describe a long-only mandate for high-net-worth and institutional investors. There is no public reference to short-selling, leverage, or hedge-fund structures.

### How does the physician-led research model work in practice?

Palo Alto Investors embeds physicians directly within the investment team, a structure established at the firm's 1989 founding. The MDs contribute clinical and scientific expertise to the fundamental research process, with the goal of generating medical and biological insights that give the team an edge in evaluating public companies — particularly in healthcare and life sciences.

## Related profiles

- [Palm Tree Crew Investments](https://altss.com/profile/palm-tree-crew-investments)
- [Palo Duro Capital](https://altss.com/profile/palo-duro-capital)

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Last updated: 2026-06-03T20:00:00.000Z

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