# Palo Santo Venture Fund

Palo Santo Venture Fund is a Venture Capital based in Highland Park, United States.

## Overview

- **Organization type:** Venture Capital
- **Headquarters:** Highland Park, United States
- **Region:** North America
- **Address:** Highland Park, IL, United States
- **Founded:** 2020
- **Assets under management:** Undisclosed
- **Website:** www.palosanto.vc
- **LinkedIn:** https://www.linkedin.com/company/palosantovc

## Regulatory record

- **Reports private funds:** No

## About

Palo Santo Venture Fund is a private equity firm based in Highland Park, US. It pursues a Venture Capital strategy, managing approximately $50 million in assets. The firm has $14.85 million in dry powder and employs 5 staff, including 5 investment professionals.

## Sectors

- Digital Health
- Neuroscience

## Questions

### What is Palo Santo’s investment focus?

Palo Santo targets the neuroscience and mental health landscape, with a focus on novel CNS therapeutics. This includes next-generation psychedelic therapies advancing through clinical trials and technologies that aim to accelerate precision neuroscience. It invests across stages, from early-stage companies to those with FDA Breakthrough Therapy Designation.

### Does Palo Santo focus on psychedelic medicine?

Palo Santo explicitly invests in next-generation psychedelic therapies that are advancing through late-stage clinical trials. It cites multiple programs that have received FDA Breakthrough Therapy Designation, showing significant and durable symptom reduction across depression, PTSD, and women’s mental health. This is one component of its broader CNS and mental health mandate.

### Who runs investment decisions at Palo Santo?

The firm has not published individual names, titles, or biographical details for its principals or investment committee. Its website states that the team brings decades of experience in neuroscience, biotech operations, investing, and clinical development, supported by leading academics and scientific advisors, but specific decision-makers are not publicly disclosed.

### How is Palo Santo structured as an investor?

The firm presents itself as a dedicated venture fund investing across the neuroscience and mental health landscape. It has not disclosed its fund structure, asset size, or whether it operates through committed capital vehicles, special purpose vehicles, or direct balance-sheet investing. Public information is limited to its investment mandate.

### Which mental health indications does Palo Santo target?

Palo Santo’s stated focus covers companies working on treatments for depression, PTSD, and women’s mental health. It cites these as areas where novel therapies have shown significant and durable symptom reduction in clinical trials. The firm also references broader brain health innovation beyond these specific indications.

## Related profiles

- [Palomar Ventures](https://altss.com/profile/palomar-ventures)
- [Palrecha Capital](https://altss.com/profile/palrecha-capital)

---

Last updated: 2026-06-03T20:00:00.000Z

Canonical page: https://altss.com/profile/palo-santo-venture-fund

Maintained by Altss — https://altss.com — methodology: https://altss.com/methodology