# Scripps Center for Mass Spectrometry and Metabolomics

Scripps Center for Mass Spectrometry and Metabolomics is a Mass Spectrometry and Metabolomics based in La Jolla, United States.

## Overview

- **Organization type:** Mass Spectrometry and Metabolomics
- **Headquarters:** La Jolla, United States
- **Region:** North America
- **Address:** La Jolla, CA, United States
- **Assets under management:** Undisclosed
- **Website:** https://masspec.scripps.edu

## Regulatory record

- **Reports private funds:** No

## About

The Scripps Center for Mass Spectrometry and Metabolomics operates within The Scripps Research Institute, a non-profit biomedical research organization headquartered in La Jolla, California. Founded as a specialized mass spectrometry facility, the center under director Gary Siuzdak has become a global reference for metabolomics methodology — particularly untargeted metabolomics, the broad-spectrum analysis of small molecules in biological samples. The center's core work involves developing and applying mass spectrometry and nuclear magnetic resonance technologies to profile metabolites, lipids, and other small molecules. It offers fee-for-service analysis, collaborates with academic and pharmaceutical partners on drug metabolism and biomarker discovery, and supports research at Scripps and externally. Known platforms include the METLIN metabolite database, curated and maintained by the center, which aggregates tandem mass spectrometry data for over 1.6 million molecular standards. Geographic reach is primarily domestic through collaborations, though METLIN and publications serve a global user base. No verifiable data exists on total expenditures, annual budget, or professional headcount. The center is funded through The Scripps Research Institute's grants and contracts, including from the National Institutes of Health. No adjacent investment vehicles, philanthropic arms, or operating businesses are reported. The unique structural characteristic of the center is its hybrid role as both an internal research core facility for Scripps scientists and a public resource that maintains and distributes a widely-used metabolomics database. It functions as an academic service center, not a financial entity, which distinguishes it from the usual profile of institutional allocators or family offices.

## Sectors

- Healthcare Services

## People

- Gary Siuzdak — Director

## Questions

### What does the Scripps Center for Mass Spectrometry and Metabolomics actually do?

It is a specialized research core facility within The Scripps Research Institute that develops and applies mass spectrometry and NMR technologies to study metabolites and small molecules. Its primary outputs include the METLIN metabolite database, fee-for-service analytical services, and collaborative research with academic and pharmaceutical partners.

### Who leads the center?

Gary Siuzdak has directed the center since its founding. He is also a professor at Scripps Research and the lead investigator on multiple NIH grants funding the center's work in metabolomics and mass spectrometry.

### How is the center funded?

The center is supported primarily by The Scripps Research Institute's institutional budget and external grants, including significant funding from the National Institutes of Health. It also generates revenue through fee-for-service analytical contracts with external collaborators.

### What is METLIN, and why is it important?

METLIN is a curated tandem mass spectrometry database maintained by the center that contains over 1.6 million molecular standards. It is widely used by researchers worldwide to identify metabolites in complex biological samples, serving as a foundational reference for untargeted metabolomics studies.

### What investment stages or sectors would this center be relevant to?

The center is not an investor. It is relevant to healthcare and life science investors, particularly in diagnostics, precision medicine, and therapeutic development, as its technology and databases directly support biomarker identification and drug metabolism analysis.

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Last updated: 2026-06-03T20:00:00.000Z

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