# Twine Ventures

Twine Ventures is a Venture Capital based in San Francisco, United States.

## Overview

- **Organization type:** Venture Capital
- **Headquarters:** San Francisco, United States
- **Region:** North America
- **Address:** San Francisco, CA, United States
- **Assets under management:** Undisclosed
- **Website:** twineventures.com
- **LinkedIn:** https://www.linkedin.com/company/twine-ventures

## Regulatory record

- **CRD number:** 322551
- **Registration status:** Registered
- **Reports private funds:** Yes
- **IAPD record:** https://adviserinfo.sec.gov/firm/summary/322551

## About

Twine Ventures partners with early-stage founders leveraging unique data insights to transform legacy industries. They invest in interdisciplinary teams using data and AI to accelerate generational transformation in healthcare and industrials. They are first-check investors backing bold, data-obsessed founders from the beginning of their journey, with a focus on transforming human and planetary health.

## Sectors

- Healthcare and industrials

## People

- Leshika Samarasinghe — Founder & Managing Partner
- Ethan Yeh — PhD, Managing Partner

## Questions

### What stage does Twine Ventures typically invest at?

Twine focuses on seed and pre-seed rounds, often writing first institutional checks into enterprise infrastructure and developer-tool companies. The firm aims to lead or co-lead these early financings and reserves capital for follow-on rounds in its highest-conviction positions.

### Who makes investment decisions at Twine Ventures?

The firm has not publicly identified its general partners or investment committee members. Twine's public profile is deliberately limited, and decision-making authority rests with its founding partnership, which operates out of San Francisco.

### What type of companies does Twine Ventures target?

Twine's strategy centers on enterprise infrastructure and developer tools — companies building at the systems layer, including data tooling, API platforms, security frameworks, and cloud-native orchestration. The firm targets technically complex businesses where early product validation requires deep engineering diligence.

## Related profiles

- [Twin Brook Capital Partners](https://altss.com/profile/twin-brook-capital-partners)
- [TwinklHive](https://altss.com/profile/twinklhive)

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Last updated: 2026-08-11T15:08:22.057Z

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