Asset Manager

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Hyloris Pharmaceuticals

Hyloris was co-founded by CEO Stijn Van Rompay and CBDO Thomas Jacobsen, both alumni of the Belgian generics company Docpharma and its successor Alter...

Hyloris Pharmaceuticals

Hyloris was co-founded by CEO Stijn Van Rompay and CBDO Thomas Jacobsen, both alumni of the Belgian generics company Docpharma and its successor Alter Pharma. The company emerged from the same network that produced Uteron Pharma, a women's-health innovator, and operates from Liege, Belgium. Its board is anchored by pharmaceutical veterans including Leon Van Rompay, founder of the listed generics firm Docpharma, and Revital Rattenbach, founding CEO of the clinical-stage biotech 4P Pharma. The company's strategy centers on reformulation and repurposing of approved molecules via the FDA's 505(b)(2) pathway and equivalent frameworks in Europe and other regions. Its declared pipeline spans cardiovascular, pain management, and infectious disease—28 disclosed programs including Sotalol IV for atrial fibrillation, Maxigesic IV for post-operative pain, and Podofilox Gel for HPV-related warts. Hyloris commercializes through licensing and co-development agreements with distribution partners rather than maintaining a direct sales organization, a structure that keeps fixed costs low while enabling simultaneous advancement of early-, mid-, and late-stage assets. The company has not disclosed total deployment or AUM, consistent with its operating-company rather than fund-manager posture. Hyloris is a Euronext Brussels-listed entity with a public-market capital structure, not a pooled investment vehicle. Its management committee of five—including CFO Christophe Maréchal, COO Dietmar Aichhorn, and CLO Ann De Jaeger—reports to a six-member board chaired by Stefan Yee. In mid-2024, Thomas Jacobsen stepped into a co-CEO role before returning to his CBDO position by November 2025, a leadership adjustment the company disclosed in its governance materials. The firm publishes an ESG report but does not identify affiliated foundations or co-investment clubs. Hyloris differs structurally from most pharma-developer peers in its reliance on abbreviated regulatory pathways to convert established molecules into patentable, differentiated products. While generic companies compete on price and novel-drug companies carry full clinical-trial risk, Hyloris occupies a middle lane—using known safety profiles to reduce development cost and time, then monetizing through royalty-bearing partnerships. Its 30-plus-asset pipeline, breadth of therapeutic coverage, and public-company transparency make it an unusual platform for investors seeking exposure to late-stage biotech cash flows without single-asset binary risk.

General information

Firm type

Asset Manager

Year founded

AUM

Undisclosed

Location

Region

Europe

Country

Belgium

City

Liege

Corporate office

Liege, Belgium

Principals

Stijn Van Rompay

Chief Executive Officer & Co-Founder

Thomas Jacobsen

Chief Business Development Officer & Co-Founder

Christophe Maréchal

Chief Financial Officer

Dietmar Aichhorn

Chief Operating Officer

Ann De Jaeger

Chief Legal Officer and General Secretary to the Board

Stefan Yee

Chairman and Non-Executive Director

Leon Van Rompay

Non-Executive Director

Mélanie Mestdagt

Non-Executive Independent Director

Vincent Van Dessel

Non-Executive Independent Director

Revital Rattenbach

Non-Executive Independent Director

Sector focus

Healthcare Services

Frequently asked questions

How does Hyloris Pharmaceuticals source its drug candidates?

Hyloris identifies approved molecules with established safety profiles that can be reformulated or repurposed to address unmet medical needs. The company's co-founders draw on decades of generics-industry experience—dating back to Docpharma and Alter Pharma—to evaluate licensing opportunities and in-license suitable assets, while also advancing internal early-stage development programs. The firm does not publicly disclose specific sourcing partners or deal structures.

What regulatory pathway does Hyloris rely on, and why does it matter?

Hyloris primarily uses the FDA's 505(b)(2) pathway in the United States and equivalent frameworks in other regions. This pathway allows the company to reference existing safety and efficacy data for the active ingredient, reducing the volume of new clinical trials required and compressing development timelines. For investors, the 505(b)(2) route lowers both the cost of development and the risk of outright clinical failure compared with novel-drug programs.

Is Hyloris a pharmaceutical manufacturer or a development platform?

Hyloris is a development and IP-licensing platform, not a manufacturer or distributor. It reformulates and repurposes existing drugs, then partners with commercial entities that handle manufacturing, marketing, and sales under license or co-development agreements. This asset-light model keeps Hyloris's fixed-cost base low while providing a royalty or milestone-based revenue stream.

How is Hyloris funded, and who governs it?

Hyloris is a publicly traded company listed on Euronext Brussels and raises capital through equity markets. Its board of directors comprises six members chaired by Stefan Yee, a private-equity investor with a background at KPMG and Linklaters. Day-to-day operations are run by a five-person executive management team led by CEO Stijn Van Rompay. The company does not operate a fund structure or manage third-party capital.

What is Hyloris's relationship with the Van Rompay family's earlier pharmaceutical ventures?

Co-founder and CEO Stijn Van Rompay was previously CFO and later CEO of Docpharma, the generics company founded by Leon Van Rompay, who now serves as a non-executive director at Hyloris. Stijn and Thomas Jacobsen later co-founded Alter Pharma before launching Hyloris. The firm is a distinct, independent entity, but its leadership team and board carry deep ties to the Belgian generics ecosystem built by the Van Rompay family and their associates.

Profile maintained by using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.

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