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450 Ventures
450 Ventures is the corporate venture arm of Blue Cross and Blue Shield of Alabama. Founded in 2017 in Birmingham, Alabama, it invests in early-stage...
Overview
450 Ventures is the corporate venture arm of Blue Cross and Blue Shield of Alabama. Founded in 2017 in Birmingham, Alabama, it invests in early-stage healthcare technology startups. 450 Ventures has made six investments, including a Series C investment in Codoxo on December 17, 2025.
General information
Firm type
Venture Capital
Year founded
2017
Location
Region
North America
Country
United States
City
Kansas City
Corporate office
Kansas City, Austin, United States
Additional offices
Austin, TX
Frequently asked questions
Where does 450 Ventures invest geographically?
The firm operates from Kansas City and Austin, concentrating on companies in the Midwest and Texas. This bi-city footprint gives it access to venture ecosystems that sit outside the dominant Bay Area, New York, and Boston hubs — regions where capital remains comparatively scarce relative to the density of technical talent and corporate innovation activity.
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