C.E. and S. Foundation

David A. Jones co-founded Humana Inc. in 1961, initially as a nursing home company called Extendicare before pivoting into hospital management and eventually health insurance. Under his leadership, Humana became one of the largest hospital corporations in the United States before its transformation into a managed-care organization. Jones served as CEO until 1997 and remained Chairman until 2005, building the Fortune 500 enterprise that ultimately funded the foundation's endowment.

David A. Jones Jr. serves as Treasurer and Officer of the C.E. and S. Foundation while simultaneously acting as Chairman and Managing Director of Chrysalis Ventures, a Louisville-based venture capital firm founded in 1993. This dual role is unusual: Jones Jr. oversees grantmaking from the family's philanthropic capital while deploying venture investments into growth-stage companies, primarily in the healthcare and technology sectors throughout the Midwest and South. Both entities operate from the same PNC Tower office suite in downtown Louisville.

The foundation's grantmaking is almost entirely restricted to Louisville, Kentucky, and its immediate metropolitan area. Its stated mission focuses on enhancing living conditions and prospects for Louisville residents, and its four program areas — caregiver engagement, social-emotional and academic support, family stability, and postsecondary education success — are all implemented through local organizations. There is no evidence of international grantmaking or significant funding directed to other US regions.

The C.E. and S. Foundation and Chrysalis Ventures share common leadership through David A. Jones Jr. and occupy the same office address at PNC Tower in Louisville. However, they operate as legally distinct entities: the foundation is a 501(c)(3) charitable organization making grants, while Chrysalis Ventures is a for-profit venture capital firm managing external limited partner capital. The foundation does not invest in Chrysalis funds as part of its endowment management, and the two organizations maintain separate programmatic and investment operations.

While the foundation's specific asset allocation is not publicly disclosed, its modest estimated endowment of approximately $72 million suggests it likely maintains a conservative, income-oriented portfolio consistent with private foundation payout requirements. Unlike large institutional endowments that pursue diversified investment strategies across public equities, private equity, and hedge funds, the C.E. and S. Foundation's focus on annual grantmaking from a smaller base implies a more liquid, lower-risk investment posture.

The foundation's known professional staff includes Nicole Eovino Diebold, who participates in the Out-of-School Time Impact Group of Grantmakers for Education, and Tess McNair, who has presented at National Center for Family Philanthropy events. However, the foundation does not publish a full staff directory, and its organizational structure appears lean relative to its grantmaking volume — characteristic of family-led foundations where principals maintain direct oversight of funding decisions rather than delegating to professional program officers.

The foundation's name refers to family members of its founder, David A. Jones Sr., though the foundation itself does not publicly decode the initials in its official communications or IRS filings. This naming convention — using family initials rather than a descriptive label — is common among private foundations where the founding family intends to maintain multi-generational control over governance and grantmaking priorities.