Nest.Bio Ventures

Nest.Bio Ventures

Weis and his partners — Cheryl Cui, Hingge Hsu, and Daphne Teo with venture partners Xi Chen, Steven Landau, and Jeffrey Lu — founded Nest.Bio in 2018. The firm operates from Cambridge, Massachusetts, the densest biotechnology cluster in the United States. Unlike most venture franchises that raise blind-pool funds and source deals through networks, Nest.Bio builds its pipeline by offering private wet-lab and office space to therapeutics startups, then selecting residents for direct investment. Nest.Bio targets therapeutics companies at seed, start-up, and expansion stages. It invests from a dedicated venture vehicle while Hatch.Bio Labs, its sister real-asset entity, leases shared and private labs in Kendall Square. The structure gives Nest.Bio early visibility into tenant progress — burn rates, hiring velocity, assay data — before making funding decisions. The resident and graduate community has grown past 50 companies and created more than 1,000 local jobs; alumni collectively hold over $7 billion in market capitalization. The firm's website flags a team background spanning machine learning, immunotherapy, and synthetic biology, suggesting active coverage of tech-bio and precision-medicine disciplines. Nest.Bio does not publicly disclose assets under management or total capital deployed. Its website highlights a dual operating-company and investment-vehicle architecture, with Hatch.Bio Labs serving as the lab-operations entity under the same Partner group. The team lists four partners, three venture partners, and one advisor — a lean structure consistent with an operator-heavy model that sources investments through tenancy rather than traditional fund-raising roadshows. Daphne Teo also serves as CEO of NSG BioLabs, a Singapore-based co-working lab platform, hinting at a potential parallel model in Asia. Nest.Bio's structural differentiator is the fusion of a real-estate operating business with a venture portfolio: it collects lab rent while earning equity upside from the same tenants. That hybrid design gives it a proprietary sourcing lane that pure financial venture firms cannot replicate without building physical infrastructure, and it concentrates the partnership's time on companies they can observe day to day rather than on external deal origination.