Venture Capital

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Ofir SouthUp Ventures

Dr. Ami Appelbaum chairs Ofir SouthUp Ventures, a Western Negev impact fund investing pre-seed to Series A in startups that relocate to Israel's Gaza envelope.

Ofir SouthUp Ventures logo

Ofir SouthUp Ventures

Ofir SouthUp Ventures is a private equity firm based in Ashkelon, Israel. It focuses on venture capital investments.

General information

Firm type

Venture Capital

Year founded

2024

AUM

Undisclosed

Location

Region

Middle East

Country

Israel

City

Sha'ar HaNegev

Corporate office

Sha'ar HaNegev Regional Council, D.N. Hof Ashkelon, 78100, Israel

Principals

Dr. Amiram (Ami) Appelbaum

Chairman

Itai Horstock

Managing Partner

Gil Shvartzman

Founding Partner

Shahar Belkin

Founding Partner

Yair Estline

Founding Partner and Legal Counsel

Rafi Nevo

Partner

Sector focus

AgriTech & FoodTechCleanTechIoTRobotics & AutomationDigital HealthClimateTechEnterprise Software

Frequently asked questions

Who runs investment decisions at Ofir SouthUp Ventures?

The Investment Committee is chaired by Dr. Amiram (Ami) Appelbaum, the former Chief Scientist and Chairman of the Israel Innovation Authority. Managing Partner Itai Horstock, who previously founded Sherpa Group and worked as an M&A attorney at Shearman & Sterling in New York, leads execution from the GP side. Founding Partner Gil Shvartzman, CEO of the SouthUp incubator, and Partners Rafi Nevo and Amichai Steimberg round out the committee alongside operating executives from the region's industrial base.

How does the fund source proprietary deal flow?

Ofir SouthUp Ventures sits atop the SouthUp incubator, which has graduated 60 startups since 2017 and maintains an active pipeline of 27 portfolio companies. Deal flow funnels through the incubator's two physical campuses in Sha'ar HaNegev and Kibbutz Nir Am, collaborations with Sapir College, and a government mandate that channels Israel Innovation Authority-backed startups into the program. The fund also allocates up to 15% of capital to exceptional startups outside the Western Negev.

Is Ofir SouthUp Ventures a single family office or a venture firm?

It operates as a private equity vehicle structured as a regional impact fund, not a family office. The GP was established by the SouthUp technology incubator and raises discretionary LP capital alongside the concessional grant layer provided by the Israel Innovation Authority. The firm pursues market-rate returns, but its mandate is geographically constrained to the Western Negev.

Does the fund participate in fund commitments or only direct deals?

The firm makes direct equity investments in startups, primarily at pre-seed, seed, and Series A stages. There is no public evidence of fund-of-funds commitments or LP positions in external GPs. The Israel Innovation Authority's grants flow to the portfolio companies themselves, not to the fund.

What is the connection between the fund and the late Ofir Libstein?

Ofir Libstein served as head of the Sha'ar HaNegev Regional Council and was the primary political force behind bringing technology entrepreneurship to the Western Negev. He was killed on October 7 while defending Kibbutz Kfar Aza. The fund is named for him and was designed to execute his vision: transform the Gaza envelope into a tech employment hub that delivers both economic resilience and returns.

Does Ofir SouthUp Ventures have a philanthropic arm?

The fund itself is not a philanthropic vehicle — it is structured to generate private market returns. However, its economic development mandate blurs the line: portfolio companies must operate in or relocate to the Western Negev, and the incubator receives state grants explicitly designated for regional revitalization. A separate nonprofit entity, the Association for the Development of Technological Entrepreneurship in the Negev Gate, runs the incubator's public-interest activities.

What is the firm's known posture on co-investments alongside external GPs?

The fund has not publicly disclosed a formal co-investment program for outside GPs. Its capital structure integrates Israel Innovation Authority grants at the company level, which would likely complicate side-by-side direct co-investments. The firm's own materials emphasize the incubator's internal network and its circle of regional industrial partners as co-investment conduits.

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