Foundation

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Alpha-1 Foundation

Committed to finding a cure for Alpha-1 and to improving the lives of people affected by Alpha-1 worldwide. | The Alpha-1 Foundation (A1F) is committed to...

Alpha-1 Foundation logo

Alpha-1 Foundation

Committed to finding a cure for Alpha-1 and to improving the lives of people affected by Alpha-1 worldwide. | The Alpha-1 Foundation (A1F) is committed to finding a cure for Alpha-1 Antitrypsin Deficiency (Alpha-1) and to improving the lives of people affected by Alpha-1 worldwide. A1F is a not-for-profit Florida corporation founded in 1995 by John Walsh, Sandy Lindsey, and Susan Stanley, three individuals diagnosed with Alpha-1. A majority of the Board of Directors are either diagnosed with Alpha-1 or have a family member diagnosed with Alpha-1.

General information

Firm type

Foundation

Year founded

1995

Location

Region

North America

Country

United States

City

Coral Gables

Corporate office

Coral Gables, FL, United States

Principals

John Walsh

Co-Founder

Sandy Lindsey

Co-Founder

Susan Stanley

Co-Founder

Sector focus

Healthcare ServicesDigital Health

Frequently asked questions

Who controls the investment decisions at Alpha-1 Foundation?

The foundation does not publicly disclose a named investment committee or CIO. Its research funding is overseen by the Board of Directors, a majority of whom are diagnosed with Alpha-1 or have an affected family member (per the firm's website). No separate investment office or external manager is identified.

How does Alpha-1 Foundation allocate its capital?

The foundation exclusively allocates capital to research grants and programs, with $100 million invested across 130 institutions in North America, Europe, the Middle East, and Australia (per the firm's website). It does not maintain separate endowment-like investment assets or direct private equity positions.

What is the relationship between Alpha-1 Foundation and pharmaceutical companies?

The foundation collaborates with the pharmaceutical industry to develop new therapies, working alongside the NIH and FDA (per the firm's website). It also participates in industry liaison groups to advance clinical development. The foundation does not disclose specific licensing or royalty arrangements.

Does Alpha-1 Foundation operate as a family office?

No. The Alpha-1 Foundation is a not-for-profit disease foundation, not a family office. It supports research and advocacy for Alpha-1 Antitrypsin Deficiency, and it is governed by a patient-majority board.

Which institutions does Alpha-1 Foundation fund?

The foundation supports research at 130 institutions across North America, Europe, the Middle East, and Australia (per the firm's website). Specific grantees are not listed on the public site, but the foundation states it works closely with the NIH, FDA, and pharmaceutical partners.

Are there any known recent changes in foundation leadership?

The last publicly noted death of a founder was John Walsh in 2017 (per the firm's website). Current leadership is not disclosed on the foundation's website beyond the board structure.

What geographic regions does Alpha-1 Foundation focus on?

The foundation funds research in North America, Europe, the Middle East, and Australia (per the firm's website). Its advocacy and program reach are global, but most grants appear concentrated in the United States and Europe.

Profile maintained by using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.

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