Single Family Office

Updated:

The Mito Fund

The Mito Fund is a venture philanthropy initiative based in Pittsburgh, Pennsylvania. It primarily supports biomedical research focused on developing...

The Mito Fund

The Mito Fund is a venture philanthropy initiative based in Pittsburgh, Pennsylvania. It primarily supports biomedical research focused on developing treatments for mitochondrial diseases. The organization has made 4 investments, including a Series A - II investment in Pretzel Therapeutics on July 11, 2025.

General information

Firm type

Single Family Office

Year founded

AUM

Undisclosed

Location

Region

North America

Country

United States

City

Corporate office

Principals

Friederike Fabritius

Founder

Sector focus

Life SciencesDigital Health

Frequently asked questions

Who runs investment decisions at The Mito Fund?

Friederike Fabritius, the fund's founder, leads investment decisions. She brings a neuropsychology background from McKinsey and co-founded the consulting firm Fabritius & Partner, which informs her scientific due-diligence approach in mitochondrial therapeutics.

How does The Mito Fund source proprietary deal flow?

The fund sources through academic mitochondrial biology networks and European-US biotech hubs, rather than through generalist venture channels. Fabritius's scientific background and the fund's narrow thesis attract founders working specifically on mitochondrial mechanisms, generating referral-based deal flow from research institutions.

Is The Mito Fund structured as a single family office or does it operate more like a venture firm?

It is structured as a single-family office — there is no evidence of external limited partners, closed-end fund vehicles, or capital-raising from institutional investors. The fund's lack of external LP pressure allows it to hold concentrated, long-duration positions in preclinical science that traditional venture funds typically avoid.

What investment stages does The Mito Fund typically target?

The fund targets preclinical and early clinical-stage companies — before conventional biotech venture funds typically engage. Its portfolio includes Phase 1 and Phase 2 clinical assets focused on mitochondrial dysfunction, with confirmed exposure to companies like Stealth Biotherapeutics during their mid-stage development.

Which sectors does The Mito Fund explicitly avoid?

The fund avoids any therapeutic area not directly linked to mitochondrial biology. This means it does not invest in oncology, immunology, or medical devices unless the mechanism specifically implicates mitochondrial dysfunction. This deliberate exclusion concentrates risk within a single biological pathway.

Profile maintained by using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.

Need institutional-grade insight on family offices?

Altss delivers:

Principals with verified direct contactsAllocation history by asset classOSINT-derived deal signals
Book a demo

Prefer a guided tour?

We’ll walk you through:

Interactive funding timelinesCustom mandate & allocation filters
Book a demo

Browse by category

More Single Family Office profiles