Venture Capital

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Originate Ventures

Originate Ventures is a venture capital firm based in Bethlehem, PA, focusing on early-stage investments in Pennsylvania and surrounding regions.

Originate Ventures logo

Originate Ventures

Originate Ventures is a venture capital firm based in Bethlehem, PA, focusing on early-stage investments in Pennsylvania and surrounding regions. The firm has made 35 investments, including an unattributed investment in HSAstore.com on January 1, 2023. Originate Ventures has facilitated 5 portfolio exits, with Adhezion Biomedical exiting on June 22, 2023.

General information

Firm type

Venture Capital

Year founded

2006

AUM

Undisclosed

Location

Region

North America

Country

United States

City

Bethlehem

Corporate office

Bethlehem, PA, United States

Principals

Glen R. Bressner

Managing Partner

Mike Gausling

Managing Partner

Eric Arnson

Partner

Sector focus

Healthcare ServicesIndustrial TechEnterprise SoftwareFinTechReal Estate

Frequently asked questions

Who runs investment decisions at Originate Ventures?

Investment decisions are led by Managing Partners Glen R. Bressner and Mike Gausling. Bressner has been a venture investor since joining Key Venture Capital in 1984 and was a partner at Mid-Atlantic Venture Funds from its 1985 founding. Gausling joined after co-founding OraSure Technologies, which he grew to a public company with a market cap exceeding $500 million.

What is Originate Ventures' geographic focus?

The firm concentrates on emerging companies in Pennsylvania and New Jersey. Its headquarters is in Bethlehem, Pennsylvania, and both Bressner and Gausling hold board and advisory roles tied to the Greater Philadelphia and Lehigh Valley economic development ecosystems.

What investment stages does Originate Ventures target?

The firm targets early-stage, growth, management buyout, and turnaround situations. This flexibility reflects the blended background of the partnership — Bressner's institutional venture experience and Gausling's operational track record navigating a company from startup to public markets.

Which sectors does Originate Ventures focus on?

The firm has invested in medical devices, avionics, compound semiconductors, digital health, and financial technology. Glen Bressner's prior board seats include Innovative Solutions & Support (avionics) and St. Christopher's Hospital for Children, while Mike Gausling's operational career centered on diagnostics and medical devices at OraSure Technologies.

What is Mike Gausling's operating background?

Mike Gausling co-founded OraSure Technologies (NASDAQ: OSUR), the company that developed the first rapid oral-fluid HIV test. Over 17 years, he grew the business to more than $50 million in annual sales and a market capitalization over $500 million, raising more than $100 million from angel investors, venture capitalists, public offerings, and commercial banks along the way.

How does Originate Ventures approach portfolio company support?

The firm describes itself as 'entrepreneurs investing in entrepreneurs,' emphasizing hands-on support beyond capital. This includes advising on personnel issues, hiring, creative fundraising, and strategic planning — areas where Eric Arnson's brand-strategy background at ENVISION and McKinsey supplements the partners' operational and investment experience.

Is Originate Ventures affiliated with a larger financial institution?

No. Originate Ventures is an independent partnership. Glen Bressner combined his prior firm, Mid-Atlantic Venture Funds, with new partners to establish the firm, and Mike Gausling joined from an operating CEO background rather than from a bank or asset manager.

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