Updated:
Paradigm Health
Paradigm Health connects patients, providers, and sponsors through a research platform.
Paradigm Health
Paradigm Health connects patients, providers, and sponsors through a research platform. The platform integrates technology and services to facilitate collaboration and patient care. Founded in 2021, the company is based in Columbus, Ohio, and serves the healthcare and life sciences industry.
General information
Firm type
Asset Manager
Year founded
2021
AUM
Undisclosed
Location
Region
North America
Country
United States
City
—
Corporate office
United States
Principals
Kent Thoelke
Founder and CEO
Jonathan Hirsch
Chief Strategy and Growth Officer
Jay Trepanier
Chief Financial Officer
Elijah Meerson
Chief Technology Officer
Michelle Lee
Chief Operating Officer
Paul Kluetz, MD
Chief Medical Officer
Sector focus
Frequently asked questions
Who runs investment decisions at Paradigm Health?
Paradigm Health is led by founder and CEO Kent Thoelke, a 30-year clinical research veteran. The executive team includes a Chief Financial Officer, Jay Trepanier, who oversees financial strategy. The company is backed by institutional venture investors, but day-to-day investment decisions for the firm's own capital are not publicly detailed.
How does Paradigm Health source proprietary deal flow?
Paradigm Health sources partnerships through its provider network and technology platform rather than traditional venture deal flow. The company partners with healthcare providers, biopharma sponsors like Bristol-Myers Squibb, and academic medical centers such as Sheba Medical Center in Israel. Its incubator relationship with ARCH Venture Partners also provides strategic connections.
Is Paradigm Health structured as a single family office or does it operate more like a venture firm?
Paradigm Health is a healthcare technology company, not a family office or venture firm. It was incubated by ARCH Venture Partners and funded by a syndicate of venture capital investors. The firm operates a commercial platform connecting clinical trial stakeholders rather than managing capital for a single family.
Does Paradigm Health participate in fund commitments or only direct deals?
Paradigm Health does not function as an investment manager making fund commitments. It is an operating company that partners with biopharma sponsors and healthcare providers to improve clinical trial execution. The firm's financial model is based on platform services, not investment returns.
What investment stages does Paradigm Health typically target?
Paradigm Health is not an investment firm; it provides a clinical research platform used across trial stages. Its partnerships span from early-phase studies to large-scale pragmatic trials, as reflected in its collaborations with Bristol-Myers Squibb and its Japan-Wide Clinical Trial Network with Fujitsu.
Which sectors does Paradigm Health explicitly avoid?
The firm does not publicly disclose any sectors it avoids. Its stated focus is on making clinical trials more accessible across therapeutic areas. Based on its leadership backgrounds, it likely concentrates on oncology, given Chief Medical Officer Dr. Paul Kluetz's background at the FDA Oncology Center of Excellence, but the firm does not limit itself to a single disease area.
Where does the underlying wealth come from?
Paradigm Health is a venture-backed company, not a family office. Its capital comes from institutional investors including ARCH Venture Partners, General Catalyst, F-Prime, GV, Lux Capital, Mubadala, and the American Cancer Society's BrightEdge Fund. The firm has no disclosed wealth origin tied to a specific family or individual fortune.
Profile maintained by Altss using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.
Need institutional-grade insight on asset managers?
Altss delivers:
Prefer a guided tour?
We’ll walk you through: