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Twist Bioscience Corp.

Twist Bioscience was founded to commercialize a proprietary semiconductor-based synthetic DNA manufacturing process.

Twist Bioscience Corp.

Twist Bioscience was founded to commercialize a proprietary semiconductor-based synthetic DNA manufacturing process. The company's silicon platform miniaturizes DNA synthesis chemistry, enabling faster, more affordable, and highly scalable production of high-quality synthetic DNA. Twist serves customers in medicine, agriculture, and industrial chemicals, helping them develop products that aim to improve lives and sustainability. The company's product suite includes custom genes, oligo pools, NGS target enrichment panels and kits, variant libraries, and antibody discovery solutions. Twist's platform supports a range of applications including AI drug discovery, cancer research, agricultural biotechnology (AgBio), and infectious disease work. Known customers include Phytoform Labs, which used Twist's oligo pools to screen thousands of AI-designed DNA sequences for trait engineering and crop improvement. Twist Bioscience operates from a headquarters in South San Francisco, with additional offices in Tel Aviv, Carlsbad (CA), Boston, Portland, Singapore, Guangzhou (China), and South Korea. The company has achieved ISO 13485:2016 certification for its quality management system and ISO 27001:2022 for information security. Twist also maintains an investor relations page on its website. A key structural differentiator is Twist's silicon-based manufacturing platform, which replaces traditional column-based or plate-based DNA synthesis methods. This architecture allows Twist to offer precision at scale that competitors cannot match — translating into faster turnaround, lower cost per base, and the ability to produce custom sequences at industrial volumes.

General information

Firm type

other

Year founded

AUM

Undisclosed

Location

Region

North America

Country

United States

City

South San Francisco

Corporate office

South San Francisco, CA, United States

Additional offices

Tel Aviv, Israel · Carlsbad, CA, United States · Singapore · Guangzhou, China · Boston, MA, United States · Portland, OR, United States · South Korea

Sector focus

Synthetic BiologyDNA SynthesisGene SynthesisOligonucleotide PoolsNext-Generation SequencingTarget EnrichmentVariant Libraries

Frequently asked questions

How does Twist Bioscience's silicon platform differ from traditional DNA synthesis?

Twist uses a proprietary semiconductor-based manufacturing process that miniaturizes DNA synthesis chemistry onto a silicon chip. This allows high-throughput, parallel synthesis at scales and speeds that traditional column- or plate-based methods cannot match, enabling cost-effective custom gene fragments, oligo pools, and NGS panels.

What industries does Twist Bioscience serve?

Twist's synthetic DNA tools are used in medicine (including precision medicine, cancer research, and drug discovery), agriculture (AgBio for trait engineering and crop improvement), and industrial chemicals. The company also serves the infectious disease field and antibody discovery and development.

Has Twist Bioscience received any quality certifications?

Yes, Twist's quality management system for its NGS target enrichment panels, reagents, and kits (catalog products) as well as synthetic RNA and DNA controls is ISO 13485:2016 certified. The company is also ISO 27001:2022 certified for information security management.

What synthetic DNA products does Twist Bioscience offer?

Twist offers custom gene fragments (including multiplexed gene fragments), oligo pools, NGS target enrichment panels and kits, variant libraries, and antibody discovery solutions. They also provide synthetic RNA and DNA standards for assay development.

Does Twist Bioscience work directly with academic researchers or only commercial entities?

Twist serves both academic researchers and commercial entities. Its website offers a special 30% discount for new customers on initial multiplexed gene fragment orders, and the company provides customer support and science teams to help customize services to specific research needs.

Where are Twist Bioscience's offices located?

Twist's headquarters is in South San Francisco, CA with additional offices in Tel Aviv (Israel), Carlsbad (CA), Boston (MA), Portland (OR), Singapore, Guangzhou (China), and South Korea. There is also a European sales office.

How does Twist Bioscience ensure ethical conduct and compliance?

Twist maintains a Code of Business Conduct & Ethics aligned with principles of service, grit, impact, and trust. It consults its legal department on all written and spoken materials and public communications to ensure compliance with laws and regulations, and it strives to deal fairly with customers, partners, competitors, and the public.

Profile maintained by using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.

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