Endowment

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UCSF Foundation Investment Company

UCSF Foundation Investment Company is a San Francisco-based investment firm founded in 2015. It manages and invests the UCSF Foundation's endowed gifts and...

UCSF Foundation Investment Company

UCSF Foundation Investment Company is a San Francisco-based investment firm founded in 2015. It manages and invests the UCSF Foundation's endowed gifts and financial assets. The firm has made three investments, including a Series C - II investment in Hazel on October 27, 2022.

General information

Firm type

Endowment

Year founded

2015

AUM

$2.5B+

Location

Region

North America

Country

United States

City

San Francisco

Corporate office

San Francisco, CA, United States

Frequently asked questions

How does UCSF's research ecosystem influence its investment decisions?

UCSF's standing as the largest public recipient of NIH funding provides the investment team with direct exposure to faculty researchers, clinical trial leads, and translational science innovators. This creates proprietary insight into emerging drug development platforms, medical device technologies, and diagnostics — particularly at the early venture stage — that informs fund manager selection and, where permitted, co-investment decisions in life sciences.

Is the UCSF Foundation Investment Company's AUM publicly reported?

The foundation endowment's specific size is not routinely broken out as a standalone figure in UC Regents public filings. The combined UC system reports total managed assets exceeding $180 billion across all pools as of mid-2023, but campus-level foundation allocations are reported in aggregated tiers that do not isolate UCSF's foundation portfolio separately.

What investment stages does the foundation typically target?

The foundation engages across the full institutional spectrum, from early-stage venture capital to mature private equity buyouts. Its most differentiated exposure is concentrated in early-stage healthcare and life-sciences venture, where UCSF's academic network provides origination advantages. The portfolio also includes allocations to real assets, fixed income, and public equities to balance risk across the endowment timeline.

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