Private Equity

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WPSS.bio

Zachary Weinberg and Nat Turner run WPSS.bio, a healthtech investment firm deploying Flatiron Health exit capital into early-stage clinical data and AI...

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WPSS.bio

WPSS.bio was formed by Zachary Weinberg and Nat Turner, the repeat founders who built Flatiron Health into the dominant US oncology data platform before its 2018 acquisition. The founding event — a $1.9 billion exit to Roche — generated the firm's core capital base. Rather than declare a fixed AUM or accept outside limited partners, the founders have structured WPSS.bio as a personal investment vehicle for healthtech and adjacent infrastructure opportunities, reflecting the operator-investor model they had already practiced at Flatiron. The firm targets early-stage life-science software, clinical-research infrastructure, and AI-enabled diagnostics — a narrow corridor that maps directly to the founders' prior operational domain. Confirmed investment stages span seed through Series A, with known positions in healthcare-data platforms and workflow-automation tools serving clinical trial sponsors and provider networks. The geographic focus concentrates on US opportunities, though regulatory data infrastructure work often extends into European trial sites. WPSS.bio operates more like a holding company placing concentrated bets than a diversified venture fund, with evidence of co-investment alongside specialist healthtech funds and existing Flatiron network relationships. The investment team is lean, centered on Weinberg and Turner with no disclosed expansion to additional offices or dedicated non-investment staff. No separate philanthropic foundation or adjacent vehicle has been publicly launched under the WPSS.bio banner. The firm has not publicly disclosed recent capital raises or deployment totals, consistent with a family-office-adjacent structure that uses founder wealth rather than institutional commitments. The founders remain visible on the healthtech conference circuit, where they signal continued conviction in the application layer of clinical-data infrastructure. What distinguishes WPSS.bio structurally is its anchor in proprietary clinical-data network access. The firm's deal flow originates from the same oncology and real-world-data partnerships Flatiron Health cultivated — giving it an early look at startups tethering their growth to clinical-data integrations. This is not a traditional venture firm raising blind pools; it is a post-exit operator vehicle making concentrated, conviction-led investments where the founders' prior regulatory and data-integration experience is the actual diligence edge.

General information

Firm type

Private Equity

Year founded

AUM

Undisclosed

Location

Region

North America

Country

United States

City

New York

Corporate office

New York, NY, United States

Principals

Zachary Weinberg

Founder & Managing Partner

Nat Turner

Co-Founder & General Partner

Sector focus

Digital HealthAI/MLEnterprise Software

Frequently asked questions

Who makes investment decisions at WPSS.bio?

Zachary Weinberg and Nat Turner serve as the firm's managing partners and are the sole disclosed investment decision-makers. Both were co-founders of Flatiron Health, the oncology data platform Roche acquired for $1.9 billion in 2018. No additional investment committee members or external advisors have been publicly identified, consistent with a tight operator-investor structure.

How does WPSS.bio source its deal flow?

The firm sources primarily through the clinical-data networks and pharma sponsor relationships established during the Flatiron Health era. Weinberg and Turner retain deep ties to oncology research sites, regulatory-data consultancies, and digital-pathology vendors — channels that surface startups building infrastructure for clinical trials and real-world evidence generation. This network-based sourcing model gives the firm early visibility into healthtech companies before they reach formal institutional fundraising rounds.

Is WPSS.bio a venture capital fund or a family office?

WPSS.bio operates as a private investment vehicle funded by the founders' Flatiron Health exit proceeds, without disclosed outside limited partners — making it structurally closer to a single-family office or holding company than a traditional venture capital fund. It does not publicly report fund sizes, fee structures, or institutional LP commitments, and appears to invest on a deal-by-deal basis rather than through a blind pool.

What investment stage does WPSS.bio typically target?

The firm concentrates on seed and early-stage start-up rounds, occasionally participating in Series A financings. Its public record of investments skews toward companies still building regulatory-grade data infrastructure and clinical-validation pipelines, where early entry aligns with the founders' ability to diligence complex health-data workflows.

Does WPSS.bio invest outside the United States?

The primary investment geography is the United States, though the firm has shown awareness of European clinical-trial data infrastructure opportunities — a natural extension of the multinational trial networks Flatiron Health served. No dedicated non-US office or regional fund vehicle has been publicly disclosed.

What is WPSS.bio's relationship with Flatiron Health and Roche?

WPSS.bio is a separate entity with no publicly disclosed operational or capital relationship with Flatiron Health or Roche. The connection is historical and reputational: Weinberg and Turner built Flatiron into a dominant oncology data platform before Roche's acquisition, and their investment thesis at WPSS.bio draws on the same clinical-data infrastructure expertise.

Does WPSS.bio participate in syndicates or co-invest alongside other funds?

Yes, public deal announcements show WPSS.bio co-investing alongside specialist healthtech venture funds. The firm appears to welcome syndicate participation, particularly where co-investors bring complementary clinical-trial or regulatory expertise rather than just balance-sheet capital.

Profile maintained by using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.

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