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Twine Ventures
Twine Ventures partners with early-stage founders leveraging unique data insights to transform legacy industries. They invest in interdisciplinary teams using...
Twine Ventures
Twine Ventures partners with early-stage founders leveraging unique data insights to transform legacy industries. They invest in interdisciplinary teams using data and AI to accelerate generational transformation in healthcare and industrials. They are first-check investors backing bold, data-obsessed founders from the beginning of their journey, with a focus on transforming human and planetary health.
General information
Firm type
Venture Capital
Location
Region
North America
Country
United States
City
San Francisco
Corporate office
San Francisco, CA, United States
Principals
Leshika Samarasinghe
Founder & Managing Partner
Ethan Yeh
PhD, Managing Partner
Sector focus
Frequently asked questions
What stage does Twine Ventures typically invest at?
Twine focuses on seed and pre-seed rounds, often writing first institutional checks into enterprise infrastructure and developer-tool companies. The firm aims to lead or co-lead these early financings and reserves capital for follow-on rounds in its highest-conviction positions.
Who makes investment decisions at Twine Ventures?
The firm has not publicly identified its general partners or investment committee members. Twine's public profile is deliberately limited, and decision-making authority rests with its founding partnership, which operates out of San Francisco.
What type of companies does Twine Ventures target?
Twine's strategy centers on enterprise infrastructure and developer tools — companies building at the systems layer, including data tooling, API platforms, security frameworks, and cloud-native orchestration. The firm targets technically complex businesses where early product validation requires deep engineering diligence.
Profile maintained by Altss using OSINT (open-source intelligence), regulatory filings, licensed data partners, and verified direct submissions. Read the methodology. Last updated: . Continuous refresh with full update cycles at least every 30 days.
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