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Venture CapitalExempt Reporting Adviser · CRD 322551Private Fund Adviser

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Twine Ventures

Twine Ventures partners with early-stage founders leveraging unique data insights to transform legacy industries. They invest in interdisciplinary teams...

Overview

Twine Ventures partners with early-stage founders leveraging unique data insights to transform legacy industries. They invest in interdisciplinary teams using data and AI to accelerate generational transformation in healthcare and industrials. They are first-check investors backing bold, data-obsessed founders from the beginning of their journey, with a focus on transforming human and planetary health.

General information

Firm type

Venture Capital

Location

Region

North America

Country

United States

City

San Francisco

Corporate office

San Francisco, CA, United States

Principals

Leshika Samarasinghe

Founder & Managing Partner

Ethan Yeh

PhD, Managing Partner

Sector focus

Healthcare and industrials

Frequently asked questions

What stage does Twine Ventures typically invest at?

Twine focuses on seed and pre-seed rounds, often writing first institutional checks into enterprise infrastructure and developer-tool companies. The firm aims to lead or co-lead these early financings and reserves capital for follow-on rounds in its highest-conviction positions.

What type of companies does Twine Ventures target?

Twine's strategy centers on enterprise infrastructure and developer tools — companies building at the systems layer, including data tooling, API platforms, security frameworks, and cloud-native orchestration. The firm targets technically complex businesses where early product validation requires deep engineering diligence.

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