Asset Manager

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Leap Therapeutics

Leap Therapeutics (NASDAQ: LPTX) is a clinical-stage biopharmaceutical company acquiring and developing novel therapeutics at the leading edge of cancer...

Leap Therapeutics

Leap Therapeutics (NASDAQ: LPTX) is a clinical-stage biopharmaceutical company acquiring and developing novel therapeutics at the leading edge of cancer research.

General information

Firm type

Asset Manager

Location

Region

North America

Country

United States

City

Cambridge

Corporate office

47 Thorndike St, Suite B1-1, Cambridge, MA, 02141, United States

Principals

Douglas Onsi

President & CEO

Christopher Mirabelli

Chairman of the Board of Directors

Khing Oei

Director

Will McEvoy

Director

James Cavanaugh

Director

Thomas Dietz

Director

William Li

Director

Joseph Loscalzo

Director

Nissim Mashiach

Director

Patricia Martin

Director

Christian Richard

Director

Richard L. Schilsky

Director

Sector focus

Healthcare ServicesBiotechnology

Frequently asked questions

Who runs investment decisions at Leap Therapeutics?

Douglas Onsi serves as President and CEO, responsible for corporate strategy and pipeline development. The board of directors includes members from venture capital and investment firms, providing oversight.

What is Leap Therapeutics' lead drug candidate?

Sirexatamab (DKN-01) is a humanized monoclonal antibody targeting the DKK1 protein, in clinical development for esophagogastric, gynecologic, and colorectal cancers.

How does Leap Therapeutics source its drug targets?

Leap in-licenses or internally discovers antibodies against well-validated cancer targets. DKN-01 targets DKK1, FL-301 targets Claudin18.2, and FL-501 targets GDF-15. The company does not disclose specific licensing partners.

Is Leap Therapeutics a family office or a biotech company?

Leap Therapeutics is a publicly traded biotechnology company (Nasdaq: LPTX). It is not structured as a family office.

What investment stages does Leap Therapeutics target?

Leap is a clinical-stage biotech developing early-to-mid-phase oncology assets. It invests internal resources in its own pipeline, not external deals.

Does Leap Therapeutics invest in other companies?

No. Leap focuses entirely on advancing its own drug candidates and does not function as an investment vehicle for external firms.

Where does Leap Therapeutics' founding wealth come from?

Leap Therapeutics was founded as a venture-backed biotech. Its early investors included HealthCare Ventures, where Chairman Christopher Mirabelli is a managing director. The specific founding wealth origin is not publicly disclosed.

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